Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep596 | Reproductive and Developmental Endocrinology | ECE2021

Novel Mutations in Human Luteinizing Hormone Beta Subunit Related to Polycystic Ovary Syndrome among Sudanese Women

Essa Nidal , Rashid Abdalla Rashid Abdalla , Salaheldein Elzaki Salaheldein Elzaki

IntroductionPolycystic ovary syndrome (PCOS) is a common disorder that is not fully understood. Multiple hormonal and metabolic factors impact on disease pathophysiology resulting in various phenotypic characteristics among the PCOS population. Luteinizing hormone beta subunit (LHβ) (protein ID P01229) is mapped on (chr19p13.3) and consists of three exons. It is specific beta (β) subunit giving to LH from the anterior pituitary its specific fun...